Intestinal Amebiasis and associated risk factors among pregnant Women attending University of Maiduguri Teaching Hospital, Nigeria

  • Abubakar Abubakar University of Maiduguri
  • Habiba J. Balla University of Maiduguri
  • Idris N. Abdullahi Ahmadu Bello University, Nigeria
  • Thairu Yunusa University of Abuja
  • Maryam M. Zakari University of Abuja Teaching Hospital
  • Kabir Umar Ahmadu Bello University, Nigeria
  • Muhammad H. Musa Bayero University, Nigeria

Abstract

Background

Entameba histolytica (E. histolytica), the etiological agent of intestinal amebiasis poses significant community health concern especially in pregnant woman due to their physiological status. Pregnancy-induced immunodeficiency can lead to reduced IgA activities which makes pregnant women susceptible to penetration of intestinal mucosal linings and placental barrier especially by E. histolytica.

Objective of study

This study aimed to determine the prevalence and associated risk factors of intestinal amebiasis among pregnant women with acute diarrhea (˂3 days post onset) attending University of Maiduguri Teaching Hospital (UMTH), Maiduguri, Nigeria.

Materials and Methods

This hospital-based cross-sectional study was conducted among 200 randomly selected acute diarrheic pregnant women attending UMTH. Fresh fecal samples were collected and immediately analyzed microscopically for E. histolytica oocytes using iodine wet preparation method. Structured questionnaires were used to assess sociodemographic variables and risk factors for amebiasis. Data analysis was done using Statistical Package for Social Sciences (SPSS) version 22 (IBM, California Inc., USA).

Results

Out of the 200 fecal samples analyzed for E. histolytica, 10 (5%) were positive. Those infected by moderate E. histolytica cysts had the highest occurrence rate, 4 (40%) and least by those infected by many E. histolytica cysts, 1 (10%). E. histolytica infection was associated with rural residence (OR=6.86 [95% CI:1.42-33.2]), lower Socioeconomic status (OR=22.0 [95% CI: 4.69-103.1]) and primigravity (OR= 5.76 [95% CI:1.19-27.8]) (p˂0.05). Drinking water from borehole (OR=0.24 [95% CI: 0.06-0.95], p=0.043) and large household (OR=0.1 [95% CI: 0.02-0.41], p=0.001) were significant risk factors of intestinal amebiasis.

Conclusion 

The results indicate that E. histolytica infection is one of the etiological agents of acute diarrhea in study participants. Its recommended that pregnant women should avoid risk factors for intestinal amebiasis identified in this study.

Keywords: Immunosuppression, Amebiasis, Risk factors, Diarrhea.

 

Author Biographies

Abubakar Abubakar, University of Maiduguri

Department of Medical Laboratory Science, University of Maiduguri

Habiba J. Balla, University of Maiduguri

Department of Medical Laboratory Science, University of Maiduguri

Idris N. Abdullahi, Ahmadu Bello University, Nigeria

Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Ahmadu Bello University, Zaria Nigeria

Thairu Yunusa, University of Abuja

Department of Medical Microbiology and Parasitology, University of Abuja, Abuja

Maryam M. Zakari, University of Abuja Teaching Hospital

Department of Obstetrics and Gynecology, University of Abuja Teaching Hospital, Abuja

Kabir Umar, Ahmadu Bello University, Nigeria

Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Ahmadu Bello University, Zaria Nigeria

Muhammad H. Musa, Bayero University, Nigeria

Department of Medical Microbiology and Parasitology, Bayero University, Kano, Nigeria

Published
2020-02-26
Section
Original Research